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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c53cbd1c905ca6936030cba224edfd9cca6865bb284ab17dcea046797f33401' 
  AND token = 'cMMoMSjJwV7p2l/TA7m88+AdvxnlHrMjkunp6EL9Xiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}