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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3313967c2e4daed2486fb960b1dccb91287c0142ba43b4552b63dc7bc40382e4' 
  AND token = 'c5AguiZNbxu94C0r0ZWQ1zV2rXlYzQsjRYgcUa1O/SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}