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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02da5a96aba18951c9a6e5fd27e561163fe01211d0bb1b3b0e9c348b3a5e917c' 
  AND token = 'HPfrQv09EtftXMAvgWZQPFyrwMRfUP44m0Sb5xBDP2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}