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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601b5e26291023e6f4dd551d011e69b64d11f12a319c4587f22e739ab1645816' 
  AND token = 'pmgXES9396O3TXd1bi/f6/JhXTa3uviHzaRT/uX5wfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}