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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c321500a591cd4b57ed4ce79f158c85c8387abd4d86f6e71c3877adff643e6be' 
  AND token = 'EhB02bP/3i+T3hVMuenaI4SGD34+n9m5znNXRWVLbbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}