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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd9bb88e99826c43815c3984770879ca746b6e4e8562da73fb393ab0140b729' 
  AND token = 'fCa9xQ7/WmiKa1CUVO63VmhKN2nQfnNDD63SlDf9YjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}