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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74443a9de7e7ff5d3617e61bc21f3c39601dcf341eafddb3fed8b8c195dcbbb' 
  AND token = 'BB4nSC/O44vY9JM5NPqMwpTGmJVYBvyPOJ4qIYoKc9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}