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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4194867eb5d43c2d59b1157a570588168b41951d72f1d33bc87ab201aa2956f0' 
  AND token = 'ffjG1Nk87Su/CiqHHlCxC52lS8TaLJxD91Sx7XnhfP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}