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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58082e322f6510e28a7f74c38ae1cf2df846b40565b151eb727283204f84e4f5' 
  AND token = 'pCDYsOcTOZmZSEVUHdOnndesUXzwlYwveuaIic4Oop4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}