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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25e944a4b841cb89a6e6ad8ab5bfe55923685c5740d185b4ab4339a24ae01c1' 
  AND token = 'J9WR0MxH03jkY3rGaHjnc5qCskpPY7AybwUtzIi7UJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}