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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6fa372ee63295f25defa66e93a5f2f9024fa010f3b5daccb9e128edde46400' 
  AND token = 'jfy0TzmzRdd7pR8ljM5N8vv8KjcK3BxmeWFLw6/HFrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}