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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a879825c6cdcc114660e7a7a7bbd4f8c91932e0be2d59debe847d301ffd8c9d' 
  AND token = 'IQv0cWD15YCu23mk90B3uka+QKAnOCxX3Vn77cguCBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}