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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fc50b53f01f7f3e6976c097813a6c3277bb21906a49bbd5b503bb2fb49d48d1' 
  AND token = 'Q5rIIjWHX6DvsRb6zMSmFWfHvuGzZS2uE91avf8l46Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}