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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fb53df3e41f8c73a8b53924e893831970b7f5692b4744b720512efdad31557' 
  AND token = '45r2GE7Ece/MKpinprbTa9/zufFpogexbREBnug+acY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}