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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15b26ed25b6ed8148c7621a3a4d06c740935049db75c71de1f28b10e1dc1c0b1' 
  AND token = 'EDNoSdAZKE9o5v032beMcls4Xc7nEV0c/qjqucdRfiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}