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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca53d49a576563d6104a5a5c028263a6079b56c247a6c0bcadc143ed872afa0' 
  AND token = 'I0IKvmcACPdwCbrIzekL5tCqS+/njIjXiQqmxyOhBxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}