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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9220daf87ad9f8e42b0237e6b7405df2e49593394a2061eb682d8e658cd8e2df' 
  AND token = 'yyzV5Fd9+82ue0IpIj2vnicj+2gP4C60d6VwuSE8j00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}