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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a88c9906740f099567f503ac322fd0634c8a6d2aa111d6b5b1281536606ad2' 
  AND token = 'Uq/kWZfYgTOWxNxBEib+jpaboXnr7NrjuwXXtcESIeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}