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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b48846eba73165e57e9c3f224cb7bb6e8035b73cb3869ca1afd10101b9c3d7d' 
  AND token = 'gcbkHvgPjW1ko2FBeDCwwfYhNjUd9TP5aqECj5rDkWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}