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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c470eabcdd2fb933a436d4c2454fc06a7c6e6de3f4bef9e40013135e1a04e609' 
  AND token = 'Nn087gij/Z7ubv7M02b2gSb7jmlzJ3fcS4pPN9AHpRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}