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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd844b04f52e189db8be53d35b9a36bbb48aa706d2be1d2b8beb78198c7d266a3' 
  AND token = 'RGRhF6bx7VpdEUfZOyc8sNzI0r2kHBErwearR7MAsG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}