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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edbfbe6bf966703630bebaa9a63f503e797de07f223f2d44289df37f7f9fe0d9' 
  AND token = 'q6k6VSmD/wLz/Z6bnW43Q5tfYOzcPeVs8BKTz4Zsbr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}