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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a222404a372b1b02a759bf7420e5d22a45fd5e85e0b436181576572d0b508bb6' 
  AND token = 'H4zW6oCfge//9aUaNJaOULb3RV9AQWpZodjdlnX6cYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}