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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f92243f4a0599efd598c91a21c515dab1df0e0cdb0d07b14e415ea19f52c049d' 
  AND token = 'hPxzL/ae5Y1mhPQO/D+5r19+HByiQrQJrsWdGmm9bfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}