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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330086f8b97b009394a1c523e1151e2566f62b800cf451f3c31015b6dca7c7c1' 
  AND token = 'A421dJWGOrf4k7ewOEalPJu/rD8B2VIMJ+HtswFAsg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}