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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3377785fba3414a009351f7d1d8463bab13b2541f001b77a70323e0dcdf01269' 
  AND token = '2WT5Xoj9u4DVIP9TZK9P09cf2YDTTSWYd5xOUnMilSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}