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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e59c9f4f43fa4d835fb8a26228055e8995facd87e715abc2a1e914980babe0c' 
  AND token = 'D0XtqOcvcgclUwYlboabQ5gjj4Vc01/ZOxnnqJ3Y8XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}