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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb509ea0bc5b2636cfbc3c3a6521272d9cf590f839ae72c3720004bac2c532e4' 
  AND token = 'JW18cfc13cCqE4Gnqk0f8aYxOnbvWQXjopfAktmUsIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}