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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43999a07145fb4e864708f0798815edb2dcb87a1e68e026ad1d71714e9b8da5d' 
  AND token = 'q++ycn8gK/b8r+TlwXQrPukZ2SE/huQZT5PMCipui7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}