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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a404d82c6457085073cdceedc593ca8db0a30714bc40df2d24cf506455e3346a' 
  AND token = 'G8wxwZ0dz134611RtaKXdAwLWtLr+qmmQXkpAG/QgoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}