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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6811e040d879720f4a1970e05c44874625c827a52b4ab0aabbb8d993a3002ac' 
  AND token = 'kb/emz1VXthueCwr7RN7ZuMGJ9Sj0+5YBM/kBTy0Mas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}