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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b68178e18d7ff9ef36be17f7cd8722dfca6d24fe5001e41b0a7311d4720c21' 
  AND token = '8Mt++uN2GvvnB1aeJTC40fLSlSGRp7GQij21hm+VwRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}