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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c18d5add7e9d565c9e79a2b8bde10bbde57cf3d6006d401f4596880b2b5c48b' 
  AND token = '66VF5TKHcICNhQmp5hfn3mzpO0oNsKvQESB/MWMtfCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}