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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb3d19f434130ba67e7f706ba6ab2bf7220529087e3dfdd66d12bae88b457d3' 
  AND token = 'I02L8oQ4WeXofva1zuZFqtXfb89S2OG/XvqzQ3PBYmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}