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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165faaebce7b4bd1df1c92e473b092e9c1255a0037eb12fa0eb5efd4214c6b78' 
  AND token = 'OJNN6UbNqE57JACK/VDVQwgsyACotcKHdBuKPtJzi8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}