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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ee0fc8485f8684a3fdfd8fb1de2a942ae1261133b53d623dd99e0bb8e5133a' 
  AND token = 'OVIx7tBak2ZV00BY5PvWIhPMFQPvcG88BTAgDR9fwMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}