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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40397607b1b8593e4fc613f51bd8dabf84a8bbf2fa401ec33baf9dcfdf87a19b' 
  AND token = '/IF8YZ6bG1ZX4L1NKsCDqoCCbZ+BZIxXxUXZPbKX0qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}