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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe7f04051cc9bcdd653d99270eff51fc0cd22d50cf14d87b1c472c1053a35e22' 
  AND token = 'VaZ+klb3+x7BofwfxU4ldJBDZxrItEWlqwTXaDoWXPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}