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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4152f3993ef0c2a07b61031b13ffa275b7ad4a8b2dc21c18f3b595474e4217' 
  AND token = 'umDKeKhFSrUjNQZ8hdmsx8UmT1y88BXvoh3OeMlzEPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}