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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e784484ea95675b435fa33bf056c4f5a0a3dcb9a3a989e7a49460acaaf71c3ee' 
  AND token = 'Ym2hYNe5SpsAlq4FrQMjLBdLfhiscjYJ+Dhfs6PqJMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}