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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6a8a5c752476564c028ff07e7fe1557332630ca2f29bfe1eaaa5133a10e2c6' 
  AND token = '8uqxH+2hNvD7EdyRcFrp1Z/7fumyDUK1YfxBs6PM3xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}