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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec64cc5a13276382dbce867b24e869276618cca2d1c759b4292f017282bfc533' 
  AND token = 'YF4bfQ/ljIvARdrUQXdzTQz7UlIWx+DeJbqm81ifTVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}