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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c531dbc67d7d83c431032cdefe34be112908db4d21c0ea5acf434153d0d7507' 
  AND token = 'sxWCEfVpqyKj5NCmgB/8TkoQo+uc3dK2cdae+e7lrRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}