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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b362262870a93ba5b7355ca1c1458d29f446f40ced567be96d70d8af0f3b3b' 
  AND token = 's6b0F7Htv0VVsKxu+Xx+tJx7rWv6Dk9RvGFQG8jJ61A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}