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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b3b2a16b6f14f4d5a257e41b447ad0f26945318135715ba3ad602e71adde4f' 
  AND token = 'Qe4w7vjzGrHJS1e3dOdrMhvWG6CYynKyffCIpRyl77E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}