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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f38e302867bb8abe7d4587566feef9e3ed8b234a1f103d233c3884566626bbb' 
  AND token = 'v4ID2ymXq/js7mcsLn4GCdLEDpeMZZzsMzB465uHD48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}