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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fdd582bee58bab408bf706bc60e6bca0411c1e10ece3f5136e7e5a69997ede3' 
  AND token = 'KvIzC6SzKhrUoy8kfirJJ4LLSAtdDjnfwRGUU83n/4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}