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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e513a72b43eda09a5a1fc520cab09d1cf301c64614dbf3240c7a41420e04166' 
  AND token = 'cihGJOx5NJhIlc9jU++JYbnkQuSyh91ENczwdt3eans=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}