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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5470e6fee192c806a5767f46756d176e0a46d9373d2eca75707da0d52b4887' 
  AND token = 'yRBM3t7Q+ftvg1EIfKNd+mqW9AUhdPNeH2gfpH/PG0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}