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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe0414f9ab58ac26dbd8eac32eef8e76c21a19ca95137b8107c584db0766332' 
  AND token = 'Dj9KzgjjY0/Va0uPt80L07egPYTfR1QIqheU0R6U2B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}